Literature DB >> 7468732

Glucocorticosteroid inhibition of intraocular proliferation after injury.

Y Tano, D B Chandler, B W McCuen, R Machemer.   

Abstract

Perforating injuries were produced in the posterior segment of rabbit eyes. We studied the inhibitory effect of a slowly water-soluble corticosteroid, dexamethasone alcohol, on fibroblast growth. The treated group received a single intravitreal injection of 1 mg of the corticosteroid. The eyes were observed for four weeks. Transvitreal proliferation was significantly decreased and wound healing was delayed as compared to a control group. Inhibition of intraocular proliferation by high doses of intravitreally injected corticosteroid may be useful in the treatment of eyes with penetrating and perforating injuries.

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Year:  1981        PMID： 7468732     DOI： 10.1016/0002-9394(81)90171-9

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN： 0002-9394            Impact factor:   5.258


  12 in total

1.  Control of experimental massive periretinal proliferation by daunomycin: dose-response relation.

Authors:  P Wiedemann; M Kirmani; M Santana; N Sorgente; S J Ryan
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1983       Impact factor: 3.117

2.  Induction of interleukin-8 in human retinal pigment epithelial cells after denuding injury.

Authors:  A Yoshida; S G Elner; Z M Bian; V M Elner
Journal:  Br J Ophthalmol       Date:  2001-07       Impact factor: 4.638

3.  Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative vitreoretinopathy.

Authors:  J B Jonas; J K Hayler; S Panda-Jonas
Journal:  Br J Ophthalmol       Date:  2000-09       Impact factor: 4.638

Review 4.  Proliferative vitreoretinopathy--is it anything more than wound healing at the wrong place?

Authors:  M Weller; P Wiedemann; K Heimann
Journal:  Int Ophthalmol       Date:  1990-03       Impact factor: 2.031

5.  Experimental study on drug therapy of "traction retinal detachment" after posterior penetrating eye injury in the rabbit.

Authors:  W Behrens-Baumann; M Vogel
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1986       Impact factor: 3.117

6.  Retinal detachment with proliferative vitreoretinopathy: surgical results with scleral buckling, closed vitrectomy, and intravitreous air injection.

Authors:  P C Ho; J W McMeel
Journal:  Br J Ophthalmol       Date:  1985-08       Impact factor: 4.638

7.  Pars plana vitrectomy assisted by triamcinolone acetonide for refractory uveitis: a case series study.

Authors:  K-H Sonoda; H Enaida; A Ueno; T Nakamura; Y-I Kawano; T Kubota; T Sakamoto; T Ishibashi
Journal:  Br J Ophthalmol       Date:  2003-08       Impact factor: 4.638

8.  Inhibition of experimental intraocular proliferation with intravitreal 5-fluouracil.

Authors:  S Binder; B Riss; C Skorpik; W Kulnig
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1983       Impact factor: 3.117

9.  Taxol treatment of experimental proliferative vitreoretinopathy.

Authors:  S A Daniels; K G Coonley; M O Yoshizumi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1990       Impact factor: 3.117

10.  A pilot study of intraocular use of intensive anti-inflammatory; triamcinolone acetonide to prevent proliferative vitreoretinopathy in eyes undergoing vitreoretinal surgery for open globe trauma; the Adjuncts in Ocular Trauma (AOT) Trial: study protocol for a randomised controlled trial.

Authors:  Philip J Banerjee; Malcolm G Woodcock; Catey Bunce; Robert Scott; David G Charteris
Journal:  Trials       Date:  2013-02-13       Impact factor: 2.279
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