| Literature DB >> 7467116 |
M T Pieraggi, J De Graeve, M Julian, J C Thiers, H Bouissou.
Abstract
In the rat, prolonged administration (7 months) of Beta-Aminopropionitrile in association with a hyperlipidic diet caused the formation of widespread pronounced atheroma. The addition of Pyridinol Carbamate during the treatment minimized and retarded the appearance of lipid overload lesions. The histological modifications were found together with an increase in the free cholesterol fraction. These two observations explain the protective role of Pyridinol Carbamate on the wall of the aorta.Entities:
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Year: 1980 PMID： 7467116 DOI： 10.1007/bf00428429
Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histol ISSN： 0340-1227