| Literature DB >> 7466835 |
F W Bonner, L J King, D V Parke.
Abstract
The effect of continuous oral administration of cadium (Cd) (75 ppm) on the concentrations of zinc (ZN), Copper (CU) and iron (Fe) in the bone of rats was investigated. Accumulation of Cd in the femur was low but increased with time. After 8 weeks of Cd exposure, femur Zn and Fe levels were significantly decreased and remained low throughout the period of cadmium treatment. After 48 weeks, Cd exposed animals had Zn and Fe concentrations in the femur of 63% and 51% of controls, respectively. The femur Cu concentration was unchanged at 36 weeks but at 48 weeks it was 76% of control animals.Entities:
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Year: 1980 PMID： 7466835 DOI： 10.1016/0378-4274(80)90157-5
Source DB: PubMed Journal: Toxicol Lett ISSN： 0378-4274 Impact factor: 4.372