Literature DB >> 7466771

Miniaturized whole blood ADCC assay of depressed effector activity in cancer patients.

M Sasaki, B Looman, P I Terasaki.   

Abstract

The ADCC test has been miniaturized to use 0.05 ml of whole blood per test as ADCC effectors. A linear dose response was shown by dilutions of 0.05 ml of blood down to a 1:16 dilution. ADCC effector activities of 40 patients with lung cancer and four with leukemia were markedly less than the activity of 200 normal subjects. Melanoma patients did not have comparable statistically significant loss of ADCC activity.

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Year:  1980        PMID: 7466771     DOI: 10.1111/j.1399-0039.1980.tb00911.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  1 in total

1.  Defective neutrophil function in low-birth-weight, premature infants.

Authors:  H Al-Hadithy; I E Addison; A H Goldstone; J C Cawley; J C Shaw
Journal:  J Clin Pathol       Date:  1981-04       Impact factor: 3.411

  1 in total

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