Literature DB >> 7465492

An autosomal recessive blind mutant in the chicken.

K M Cheng, R N Shoffner, K N Gelatt, G G Gum, J S Otis, J J Bitgood.   

Abstract

A type of blindness due to lack of rods and cones in the retina was found to be controlled by a single autosomal recessive gene, rc. The mutation was first identified in the second generation descendants of a male carrying an ethyl methanesulfonate (EMS) induced chromosome translocation involving one arm of the Z sex chromosome and the long (q) arm of chromosome 3. A linkage test between the locus causing the blindness and the translocation break-point on chromosome 3 was not significant. There is no proof that the mutation was EMS induced.

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Year:  1980        PMID: 7465492     DOI: 10.3382/ps.0592179

Source DB:  PubMed          Journal:  Poult Sci        ISSN: 0032-5791            Impact factor:   3.352


  6 in total

Review 1.  Circadian phototransduction and the regulation of biological rhythms.

Authors:  Mario E Guido; Agata R Carpentieri; Eduardo Garbarino-Pico
Journal:  Neurochem Res       Date:  2002-11       Impact factor: 3.996

2.  A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype.

Authors:  S L Semple-Rowland; N R Lee; J P Van Hooser; K Palczewski; W Baehr
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-03       Impact factor: 11.205

Review 3.  Leber congenital amaurosis caused by mutations in GUCY2D.

Authors:  Shannon E Boye
Journal:  Cold Spring Harb Perspect Med       Date:  2014-09-25       Impact factor: 6.915

4.  A genetic abnormality of cardiac myocytes from the blind mutant (RC) chick heart: abnormalities of cardiac structure and choline transport.

Authors:  S W Rabkin; K M Cheng
Journal:  Basic Res Cardiol       Date:  1992 Nov-Dec       Impact factor: 17.165

5.  An x-ray scattering study into the structural basis of corneal refractive function in an avian model.

Authors:  Siân R Morgan; Erin P Dooley; Paul M Hocking; Chris F Inglehearn; Manir Ali; Thomas L-M Sorensen; Keith M Meek; Craig Boote
Journal:  Biophys J       Date:  2013-06-18       Impact factor: 4.033

Review 6.  Insights gained from gene therapy in animal models of retGC1 deficiency.

Authors:  Shannon E Boye
Journal:  Front Mol Neurosci       Date:  2014-05-14       Impact factor: 5.639

  6 in total

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