Literature DB >> 7464625

Cardiac arrest after intravenous injection of cimetidine.

R G Shaw, M L Mashford, P V Desmond.   

Abstract

Three episodes, in which patients suffered a cardiac arrest in close association with receiving a bolus intravenous injection of cimetidine, are reported. The possible role of cimetidine in causing cardiac arrest, and the mechanisms which may be involved, are discussed. It is recommended that intravenous administration of cimetidine should be an infusion performed over at least 30 minutes.

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Year:  1980        PMID: 7464625     DOI: 10.5694/j.1326-5377.1980.tb77073.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  6 in total

Review 1.  Drug effects on the electrocardiogram. A review of their clinical importance.

Authors:  J D Symanski; L S Gettes
Journal:  Drugs       Date:  1993-08       Impact factor: 9.546

Review 2.  [Histamine effects on the heart with special reference to cardiac side effects of H2 receptor antagonists].

Authors:  D Baller; H Huchzermeyer
Journal:  Klin Wochenschr       Date:  1989-08-01

3.  Comparative trial of the effect of ranitidine and cimetidine on gastric secretion in fasting patients at induction of anaesthesia.

Authors:  J M Durrant; L Strunin
Journal:  Can Anaesth Soc J       Date:  1982-09

4.  The influence of duration of intravenous infusion of an acute dose on plasma concentrations of cimetidine.

Authors:  D J Morgan; D A Uccellini; K Raymond; G W Mihaly; D B Jones; R A Smallwood
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

5.  Inotropic effects of ranitidine.

Authors:  E C Meyer; D K Sommers; M van Wyk; J C Avenant
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

6.  H2-receptor antagonism is not pro-arrhythmic in a chronic canine model.

Authors:  A C Uprichard; D W Harron
Journal:  Basic Res Cardiol       Date:  1990 Sep-Oct       Impact factor: 17.165

  6 in total

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