| Literature DB >> 7463094 |
C L King, Y C Kong, N S Wong, H W Yeung, H H Fong, U Sankawa.
Abstract
Rutaecarpine (1) and dehydroevodiamine (2) were isolated from the unripe fruit of Evodia rutaecarpa. In vitro uterotonic assay on rat uterus showed both alkaloids to be active. Dehydroevodiamine was further shown to be active in the in vivo uterotonic assay using rats as the animal model. Reference evodiamine hydrochloride (3) was also evaluated and found to be devoid of uterontonic activity at the doses administered.Entities:
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Year: 1980 PMID： 7463094 DOI： 10.1021/np50011a008
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050