Analgesia induced by nitrous oxide and oxygen as an adjunct to local anesthesia in dermatologic surgery. Results of clinical trials.

Clinical trials were carried out to determine if analgesia induced by nitrous oxide and oxygen could be useful as an adjunct to local anesthesia in dermatologic surgery. Patients readily accepted the procedure. The analgesia obtained reduced anxiety and pain, and no important adverse side effects were encountered. Overall, the agents and method are effective and have advantages over more commonly used agents and methods used as adjuncts to local anesthesia.