| Literature DB >> 7462332 |
Abstract
A continuously growing cell line (FMP1.1) has been isolated, which is dependent upon a factor in PWCM for both growth and survival. FMP1.1 appears to be a mast cell, since IgE receptors are present and their granules react specifically with a mast cell granule stain. The factor in PWCM may be a glycoprotein and has biochemical properties in common with PWCM factors, which stimulate at least four other lineages of hemopoietic colony-forming cell. This line provides a pure population of cells as a model for studying molecular events of hemopoietic precursor cell growth and differentiation.Entities:
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Year: 1980 PMID: 7462332 DOI: 10.1002/jcp.1041050221
Source DB: PubMed Journal: J Cell Physiol ISSN: 0021-9541 Impact factor: 6.384