Literature DB >> 7462295

Effect of combined surgical and chemotherapeutic treatment of Lewis lung carcinoma.

Z Szabó, O Dworák, L Kopper, K Lapis.   

Abstract

The effect of combined surgical and chemotherapeutic treatment on Lewis lung carcinoma was studied. The i.m. implanted primary tumor was removed on the 10th day after transplantation, and the survival of mice was registered. Cyclophosphamide proved to be the most effective among the drugs studied (Cyclophosphamide, 5-FU, DBD, CCNU, Adriamycin, Vincristin, Hexyldeoxyuridine). Using different schedules (pre- and/or post-operative treatment) the pre- and post-operative drug administration was the most advantageous. Combined therapy showed always better effect than monotherapy.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7462295     DOI： 10.1007/bf00409902

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  7 in total

1.  Inhibition of tumor growth in syngeneic chimeric mice mediated by a depletion of suppressor T cells.

Authors:  V Rotter; N Trainin
Journal:  Transplantation       Date:  1975-07       Impact factor: 4.939

2.  Effectiveness of clinically active antineoplastic drugs in a surgical-adjuvant chemotherapy treatment regimen using the Lewis Lung (LL) carcinoma.

Authors:  P C Merker; I Wodinsky; M L Cantor; J M Venditti
Journal:  Int J Cancer       Date:  1978-04-15       Impact factor: 7.396

3.  Correlation of immune response with clinical stage in Lewis lung tumor-bearing mice.

Authors:  T Kurata; M Micksche
Journal:  Oncology       Date:  1978       Impact factor: 2.935

4.  Pulmonary metastases of the lewis lung tumor-cell kinetics and response to cyclophosphamide at different sizes.

Authors:  R P Hill; J A Stanley
Journal:  Cancer Treat Rep       Date:  1977 Jan-Feb

5.  Effects of surgery on the cell kinetics of residual tumor.

Authors:  L Simpson-Herren; J P Holmquist
Journal:  Cancer Treat Rep       Date:  1976-12

6.  [Combination of surgery and chemotherapy in cancer; model experiment on a resistant tumor in the rat].

Authors:  H DRUCKREY; B T KUK; D SCHMAHL; D STEINHOFF
Journal:  Munch Med Wochenschr       Date:  1958-12-05

7.  Effect of various chemotherapeutic agents on metastasis.

Authors:  K LAPIS; L NEMETH
Journal:  Br J Cancer       Date:  1956-12       Impact factor: 7.640
  7 in total
  1 in total

1.  Chemotherapeutic sensitivity of liver metastases from intrasplenically-growing Lewis lung tumor.

Authors:  K Pál; L Kopper; K Lapis
Journal:  Clin Exp Metastasis       Date:  1983 Oct-Dec       Impact factor: 5.150
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.