| Literature DB >> 7461729 |
J Hopkins, I McConnell, J D Pearson.
Abstract
Prostaglandin E2 (PGE2) can mediate changes in lymphocyte traffic through lymph nodes. By measuring PGE2 levels in efferent lymph from cannulated sheep lymph nodes it was shown that increased synthesis of PGE2 always correlated with cell shutdown; infusion of PGE2 alone induced cell shutdown and inhibition of PGE2 synthesis by the node abolished cell shutdown induced by antigen.Entities:
Mesh:
Substances:
Year: 1981 PMID: 7461729 PMCID: PMC1458077
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397