Literature DB >> 7459305

Cefuroxime: potential use in pregnant women at term.

P Bousfield, A K Browning, B M Mullinger, M Elstein.   

Abstract

The placental transfer of cefuroxime was studied in 20 women after one or more 1.5 g intravenous injections. Ten women had labour induced at term and ten were delivered by elective Caesarean section. High concentrations of cefuroxime were found in the cord blood and amniotic fluid and therapeutically active antibiotic levels were found in the infants for up to six hours after delivery.

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Year:  1981        PMID： 7459305     DOI： 10.1111/j.1471-0528.1981.tb00959.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN： 0306-5456


  6 in total

Review 1.  Pharmacokinetics and tissue concentrations of cefuroxime.

Authors:  T B Vree; Y A Hekster
Journal:  Pharm Weekbl Sci       Date:  1990-12-14

2.  Pharmacokinetics of cefuroxime in pregnant patients with preterm premature rupture of the membranes.

Authors:  F J Roumen; P X Bouckaert; H M Cremers; T B Vree
Journal:  Pharm Weekbl Sci       Date:  1990-12-14

3.  Assessment of infant development during an 18-month follow-up after treatment of infections in pregnant women with cefuroxime axetil.

Authors:  W Manka; R Solowiow; D Okrzeja
Journal:  Drug Saf       Date:  2000-01       Impact factor: 5.606

4.  Transplacental transfer of cefuroxime in uncomplicated pregnancies and those complicated by hydrops or changes in amniotic fluid volume.

Authors:  D E Holt; N M Fisk; J A Spencer; J de Louvois; R Hurley; D Harvey
Journal:  Arch Dis Child       Date:  1993-01       Impact factor: 3.791

5.  Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.

Authors:  André Dallmann; Ibrahim Ince; Juri Solodenko; Michaela Meyer; Stefan Willmann; Thomas Eissing; Georg Hempel
Journal:  Clin Pharmacokinet       Date:  2017-12       Impact factor: 6.447

6.  Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section.

Authors:  Hanadi H Alrammaal; Khaled Abduljalil; Victoria Hodgetts Morton; R Katie Morris; John F Marriott; Hsu P Chong; Hannah K Batchelor
Journal:  Pharmaceutics       Date:  2022-05-30       Impact factor: 6.525
  6 in total

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