Literature DB >> 7458433

An inhibitor of leucocyte movement in the plasma of patients with rheumatoid arthritis.

J R Walker, M J Smith.   

Abstract

Plasma from patients with rheumatoid arthritis shows inhibitory activity towards the random and stimulated movement of human polymorphonuclear leucocytes and peripheral phagocytic monocytes in vitro. The inhibitory activity is heat-labile, not present in plasma from patients with noninflammatory diseases, and appears to exert its inhibitory effects by occupying sites on the cell cell membrane from where it may be removed by washing. It is suggested that this factor(s) is responsible for the diminished accumulation of polymorphonuclear leucocytes into skin chambers with occurs in patients with rheumatoid arthritis.

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Year:  1980        PMID： 7458433      PMCID： PMC1000621          DOI： 10.1136/ard.39.6.563

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  7 in total

1.  Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes.

Authors:  R D Nelson; P G Quie; R L Simmons
Journal:  J Immunol       Date:  1975-12       Impact factor: 5.422

2.  Influence of surface proteins and separation techniques on neutrophil unstimulated and stimulated locomotion in vitro.

Authors:  J E Repine; C C Clawson
Journal:  J Reticuloendothel Soc       Date:  1978-09

3.  A proposal for the definition of terms related to locomotion of leukocytes and other cells.

Authors:  H U Keller; P C Wilkinson; M Abercrombie; E L Becker; J G Hirsch; M E Miller; W S Ramsey; S H Zigmond
Journal:  J Immunol       Date:  1977-05       Impact factor: 5.422

4.  A rapid one-step procedure for purification of mononuclear and polymorphonuclear leukocytes from human blood using a modification of the Hypaque-Ficoll technique.

Authors:  A Ferrante; Y H Thong
Journal:  J Immunol Methods       Date:  1978       Impact factor: 2.303

5.  Directed migration of circulating polymorphonuclear leucocytes in patients with rheumatoid arthritis: a defect in the plasma.

Authors:  J R Walker; D W James; M J Smith
Journal:  Ann Rheum Dis       Date:  1979-06       Impact factor: 19.103

6.  A comparison of two in vitro methods for studying a defect in leucocyte movement in rheumatoid arthritis.

Authors:  J R Walker; M J Smith; D W James
Journal:  Int Arch Allergy Appl Immunol       Date:  1979

7.  Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis.

Authors:  A G Mowat; J Baum
Journal:  J Clin Invest       Date:  1971-12       Impact factor: 14.808
  7 in total
  4 in total

1.  Staphylococcal infections in childhood dermatomyositis--association with the development of calcinosis, raised IgE concentrations and granulocyte chemotactic defect.

Authors:  E C Moore; F Cohen; S D Douglas; V Gutta
Journal:  Ann Rheum Dis       Date:  1992-03       Impact factor: 19.103

2.  Subnormal sensitivity of neutrophils to complement split product C5a in rheumatoid arthritis: relation to complement catabolism and disease extent.

Authors:  J Elmgreen; T M Hansen
Journal:  Ann Rheum Dis       Date:  1985-08       Impact factor: 19.103

3.  GM-CSF and G-CSF in Felty's syndrome.

Authors:  D R Wagner; C Combe; U Gresser
Journal:  Clin Investig       Date:  1993-02

4.  In vivo crevicular leukocyte response to a chemotactic challenge: inhibition by experimental diabetes.

Authors:  L M Golub; G A Nicoll; V J Iacono; N S Ramamurthy
Journal:  Infect Immun       Date:  1982-09       Impact factor: 3.441
  4 in total

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