Treatment of dermatitis herpetiformis with colchicine.

Oral colchicine therapy was used successfully in the treatment of three patients with dermatitis herpetiformis, although the degree of disease control varied. The condition of a fourth patient did not improve. A trial of colchicine is suggested when conventional therapy with dapsone or sulfapyridine is contraindicated or when a gluten-free diet cannot be employed.