[Vaccinations therapy of laryngeal papillomatosis (author's transl)].

Our experiences with 49 cases of laryngeal papillomae of which 22 were submitted to a vaccine therapy are encouraging. 1. Tracheotomy as a remedial and therapeutic procedure is dispensable by ablation of papillomae in respiratory-laryngoscopy. 2. Additional application of a virus-vaccine contributes to healing by reducing the frequency of ablations. In few cases papilloma healed without endo-surgicals ablations after application of vaccine Charge 4. 3. 4 in 11 cases with delayed or complicated healing processes, a part of them after papillomatosis lasting for decades, could surprisingly be cured. In 2 females laryngectomy had finally to be carried out because of the development of laryngeal cancer, with and without preceeding vaccination, respectively. 4. Side-effects during and after vaccination could not be stated, five years ago. 5. We think vaccination to be an effective complement of the wellproved surgical ablation of papillomae under optimal endoscopical working conditions.