| Literature DB >> 7454219 |
Abstract
Diagnosis and therapy of retinal and uveal circulatory disorders should be based mainly on two pathophysiologic principles: (1) an autoregulation is effective in the retinal circulation only but absent in the choroidal circulation and (2) circulatory disorders may be caused not only be a reduced but also by an increased blood flow. The clinical evaluation of an individual retinal circulatory disorder depends on the interpretation of the dynamics of visual disturbances, detection of vascular type or fiber bundle defects in the visual field, repeated estimation of blood flow velocity by direct ophthalmoscopy or fluorescence angiography, and detection of specific fundus signs such as focal ischemia (cotton wool spots) or development of a collateral circulation and true neovascularization. For the indirect assessment of disturbances of the choroidal circulation certain subjective symptoms, alterations of the pigment epithelium, and edema and focal defects of the choriocapillaries are of importance. The stereobiomicroscopy of the fundus with a slitlamp and fluorescence angiographic studies of the sectorial distribution of the choroidal filling are valuable diagnostic aids.Entities:
Mesh:
Year: 1980 PMID: 7454219 DOI: 10.1159/000308961
Source DB: PubMed Journal: Ophthalmologica ISSN: 0030-3755 Impact factor: 3.250