Literature DB >> 7453823

A model from electron microscopy for the molecular structure of fibrinogen and fibrin.

J W Weisel, G N Phillips, C Cohen.   

Abstract

The overall architecture of the fibrinogen molecule and aspects of its packing to form fibrin have been derived from a study of electron microscope images of ordered arrays. The molecule, of length 450 A, is seen in more detail than the Hall-Slayter model and is made up of seven globular domains connected by rod-like segments.

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Year:  1981        PMID: 7453823     DOI: 10.1038/289263a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  14 in total

1.  A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides.

Authors:  Z Yang; I Mochalkin; R F Doolittle
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  The crystal structure of modified bovine fibrinogen.

Authors:  J H Brown; N Volkmann; G Jun; A H Henschen-Edman; C Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

3.  Visualization and identification of the structures formed during early stages of fibrin polymerization.

Authors:  Irina N Chernysh; Chandrasekaran Nagaswami; John W Weisel
Journal:  Blood       Date:  2011-01-19       Impact factor: 22.113

4.  Twisting of fibrin fibers limits their radial growth.

Authors:  J W Weisel; C Nagaswami; L Makowski
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Fibrin assembly. Lateral aggregation and the role of the two pairs of fibrinopeptides.

Authors:  J W Weisel
Journal:  Biophys J       Date:  1986-12       Impact factor: 4.033

6.  Adsorptive endocytosis of fibrin monomer by macrophages: evidence of a receptor for the amino terminus of the fibrin alpha chain.

Authors:  S R Gonda; J R Shainoff
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

7.  Structure of the fibrin protofibril.

Authors:  W E Fowler; R R Hantgan; J Hermans; H P Erickson
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

8.  Characterization of the inhibition of fibrin assembly by fibrinogen fragment D.

Authors:  J E Williams; R R Hantgan; J Hermans; J McDonagh
Journal:  Biochem J       Date:  1981-09-01       Impact factor: 3.857

9.  Band patterns seen by electron microscopy in ordered arrays of bovine and human fibrinogen and fibrin after negative staining.

Authors:  R C Williams
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

10.  Fibrin aggregation before sol-gel transition.

Authors:  P Wiltzius; G Dietler; W Känzig; V Hofmann; A Häberli; P W Straub
Journal:  Biophys J       Date:  1982-05       Impact factor: 4.033

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