Literature DB >> 7453137

Study on drug interactions.

K Venkatesan, V P Bharadwaj, G Ramu, K V Desikan.   

Abstract

Studies on the interactions of the drugs used in combination therapy of leprosy were attempted at this Institute. INH supplementation with clofazimine, therapy appeared to lower the skin levels of clofazimine, raising the plasma and urinary content of clofazimine. Concurrent administration of clofazimine with DDS does not appear to exert any influence on the excretion of DDS. The plasma DDS lowering effect of Rifampicin does not vary between fast and slow acetylators for DDS.

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Year:  1980        PMID: 7453137

Source DB:  PubMed          Journal:  Lepr India        ISSN: 0024-1024


  7 in total

1.  The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man.

Authors:  M D Coleman; A K Scott; A M Breckenridge; B K Park
Journal:  Br J Clin Pharmacol       Date:  1990-11       Impact factor: 4.335

2.  Influence of once-monthly rifampicin and daily clofazimine on the pharmacokinetics of dapsone in leprosy patients in Nigeria.

Authors:  F A Pieters; F Woonink; J Zuidema
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

Review 3.  Pharmacokinetic drug interactions with rifampicin.

Authors:  K Venkatesan
Journal:  Clin Pharmacokinet       Date:  1992-01       Impact factor: 6.447

Review 4.  Clinical pharmacokinetics of dapsone.

Authors:  J Zuidema; E S Hilbers-Modderman; F W Merkus
Journal:  Clin Pharmacokinet       Date:  1986 Jul-Aug       Impact factor: 6.447

Review 5.  Clinical pharmacokinetic considerations in the treatment of patients with leprosy.

Authors:  K Venkatesan
Journal:  Clin Pharmacokinet       Date:  1989-06       Impact factor: 6.447

6.  Comparative study of the effects of antituberculosis drugs and antiretroviral drugs on cytochrome P450 3A4 and P-glycoprotein.

Authors:  Yasuhiro Horita; Norio Doi
Journal:  Antimicrob Agents Chemother       Date:  2014-03-24       Impact factor: 5.191

Review 7.  Clinical pharmacokinetics of clofazimine. A review.

Authors:  M R Holdiness
Journal:  Clin Pharmacokinet       Date:  1989-02       Impact factor: 6.447

  7 in total

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