Literature DB >> 7450449

Sulindac (Clinoril) hepatitis.

A K Dhand, D R LaBrecque, J Metzger.   

Abstract

A patient with Sulindac-induced hepatitis is presented. Sulindac was confirmed as the cause of the patient's liver disease when hepatic dysfunction abruptly recurred after an inadvertent reexposure to Sulindac and quickly resolved when the drug was withdrawn. The prompt reappearance of fever, chills, pruritus, rash, tender hepatomegaly, and abnormal liver tests after only two doses of Sulindac suggested a hypersensitivity reaction.

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Year:  1981        PMID: 7450449

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  9 in total

Review 1.  Hepatic manifestations of autoimmune rheumatic diseases.

Authors:  S Abraham; S Begum; D Isenberg
Journal:  Ann Rheum Dis       Date:  2004-02       Impact factor: 19.103

2.  A fatal case of sulindac-induced Lyell syndrome (toxic epidermal necrolysis).

Authors:  N Ikeda; K Umetsu; T Suzuki
Journal:  Z Rechtsmed       Date:  1987

3.  Acute pancreatitis associated with long-term sulindac therapy.

Authors:  D J Zygmunt; H J Williams; S R Bienz
Journal:  West J Med       Date:  1986-04

Review 4.  Effects of non-narcotic analgesics on the liver.

Authors:  L F Prescott
Journal:  Drugs       Date:  1986       Impact factor: 9.546

Review 5.  Clinical associations between arthritis and liver disease.

Authors:  P R Mills; R D Sturrock
Journal:  Ann Rheum Dis       Date:  1982-06       Impact factor: 19.103

Review 6.  Nonsteroidal anti-inflammatory drugs. Differential use in older patients.

Authors:  L Girgis; P Brooks
Journal:  Drugs Aging       Date:  1994-02       Impact factor: 3.923

Review 7.  Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.

Authors:  A V Manoukian; J L Carson
Journal:  Drug Saf       Date:  1996-07       Impact factor: 5.606

Review 8.  Drug-induced cholestasis.

Authors:  H J Zimmerman; J H Lewis
Journal:  Med Toxicol       Date:  1987 Mar-Apr

9.  Sulindac hepatotoxicity.

Authors:  S J Whittaker; J N Amar; I R Wanless; J Heathcote
Journal:  Gut       Date:  1982-10       Impact factor: 23.059

  9 in total

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