Literature DB >> 7450320

Heterogeneity of the haemoglobin-A1c-band in isoelectric focussing.

B S Welinder, P A Svendsen.   

Abstract

A double HbA1c-band was demonstrated in isoelectric focussing of blood from diabetics with a fasting blood glucose above 11 mmol/l. The same band-doubling was also demonstrated after incubation of erythrocytes in glucose/saline solutions. This finding may reflect the presence of the initial condensation product between haemoglobin and glucose, the Schiff-base intermediate.

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Year:  1980        PMID: 7450320     DOI: 10.1007/bf00281827

Source DB:  PubMed          Journal:  Diabetologia        ISSN: 0012-186X            Impact factor:   10.122


  6 in total

1.  Further identification of the nature and linkage of the carbohydrate in hemoglobin A1c.

Authors:  H F Bunn; D N Haney; K H Gabbay; P M Gallop
Journal:  Biochem Biophys Res Commun       Date:  1975-11-03       Impact factor: 3.575

2.  Some physical measurements (weight, length, head circumference and chest circumference) in healthy Swedish children in the first two years of life.

Authors:  P KARLBERG; A PERMAN
Journal:  Acta Paediatr Suppl       Date:  1959-04-11

3.  Fast glycosylation of haemoglobin.

Authors:  P A Svendsen; J S Christiansen; B Welinder; J Nerup
Journal:  Lancet       Date:  1979-03-17       Impact factor: 79.321

4.  Synthesis of hemoglobin Aic and related minor hemoglobin by erythrocytes. In vitro study of regulation.

Authors:  K M Spicer; R C Allen; D Hallett; M G Buse
Journal:  J Clin Invest       Date:  1979-07       Impact factor: 14.808

5.  Rapid changes in chromatographically determined haemoglobin A1c induced by short-term changes in glucose concentration.

Authors:  P A Svendsen; J S Christiansen; U Søegaard; B S Welinder; J Nerup
Journal:  Diabetologia       Date:  1980-08       Impact factor: 10.122

6.  Structure of carbohydrate of hemoglobin AIc.

Authors:  R J Koenig; S H Blobstein; A Cerami
Journal:  J Biol Chem       Date:  1977-05-10       Impact factor: 5.157

  6 in total
  1 in total

1.  Labile and stable glycosylated hemoglobin during OGTT in healthy subjects and maturity-onset diabetics.

Authors:  M Trovati; R Lorenzati; S Vitali; E Guerra; S Martire; G Pagano
Journal:  Acta Diabetol Lat       Date:  1981 Jul-Sep
  1 in total

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