Literature DB >> 7450046

[Compounds with antitumor activity. V. Hydrazone derivatives of 5-formylimidazo(2,1-b)thiazoles and 6-substituted 2,3-dihydro-5-formylimidazo(2,1-b)thiazoles].

A Andreani, M Rambaldi, D Bonazzi.   

Abstract

The synthesis of 2,3-dihydro-5-formylimidazo[2,1-b]thiazoles with different substituents at position 6 (CH3, C6H5, Cl, Br) is reported; thiosemicarbazones and tosylhydrazones were prepared from these aldehydes and from the 2,3-unsaturated analogues: these derivatives, submitted to a preliminary test, did not show significant antileukemic activity.

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Year:  1980        PMID: 7450046     DOI: 10.1002/chin.198046224

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  1 in total

1.  Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.

Authors:  Roberta Budriesi; Pierfranco Ioan; Alberto Leoni; Nicoletta Pedemonte; Alessandra Locatelli; Matteo Micucci; Alberto Chiarini; Luis J V Galietta
Journal:  J Med Chem       Date:  2011-05-13       Impact factor: 7.446

  1 in total

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