Literature DB >> 7449915

In situ aging of auricular chondrocytes is not due to the exhaustion of their replicative potential.

S Moskalewski, A Gołaszewska, T Ksiazek.   

Abstract

Multiplication of chondrocytes during growth of rabbit auricular cartilage was estimated on the basis of total DNA determination and compared with the population doubling level reached by these chondrocytes in vitro. The results indicate that the in situ aging of auricular chondrocytes is caused by factors other than the intrinsic depletion of their growth potential.

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Year:  1980        PMID: 7449915     DOI: 10.1007/bf01969596

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  14 in total

1.  THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.

Authors:  L HAYFLICK
Journal:  Exp Cell Res       Date:  1965-03       Impact factor: 3.905

2.  The serial cultivation of human diploid cell strains.

Authors:  L HAYFLICK; P S MOORHEAD
Journal:  Exp Cell Res       Date:  1961-12       Impact factor: 3.905

3.  The fine structure of developing elastic cartilage.

Authors:  R W Cox; M A Peacock
Journal:  J Anat       Date:  1977-04       Impact factor: 2.610

Review 4.  The origin of the wide species variation in nuclear DNA content.

Authors:  H Rees; R N Jones
Journal:  Int Rev Cytol       Date:  1972

5.  The strategy of senescence.

Authors:  L Hayflick
Journal:  Gerontologist       Date:  1974-02

6.  Reconstruction of the elastic cartilage by isolated chondrocytes in autogeneic transplants.

Authors:  J Kawiak; S Moskalewski; A Hinek
Journal:  Acta Anat (Basel)       Date:  1970

7.  Loss of division potential in vitro: aging or differentiation?

Authors:  E Bell; L F Marek; D S Levinstone; C Merrill; S Sher; I T Young; M Eden
Journal:  Science       Date:  1978-12-15       Impact factor: 47.728

8.  Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

Authors:  G M Martin; C A Sprague; C J Epstein
Journal:  Lab Invest       Date:  1970-07       Impact factor: 5.662

9.  Maturation of rabbit auricular chondrocytes grown in vitro in monolayer culture.

Authors:  S Moskalewski; I Adamiec; A Gołaszewska
Journal:  Am J Anat       Date:  1979-07

10.  The influence of the degree of maturation of donor tissue on the reconstruction of elastic cartilage by isolated chondrocytes.

Authors:  S Moskalewski; E Rybicka
Journal:  Acta Anat (Basel)       Date:  1977
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  1 in total

1.  Rabbit chondrocytes are binucleate in auricular but not articular cartilage.

Authors:  J M Lipman; B J Hicks; L Sokoloff
Journal:  Experientia       Date:  1984-06-15
  1 in total

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