| Literature DB >> 74499 |
M L Bach, F H Bach, J M Zarling.
Abstract
It is proposed that cells cytotoxic for autologous or syngeneic tumour cells can be produced in vitro by sensitisation of lymphocytes to a pool of normal cells from 20 unrelated individuals. Restriction on molecules that can serve as cytotoxic determinants (C.D.), may explain why a random pool of cells from 20 people could present essentially all of the determinants (C.D.) may explain why a random pool of occur because of extensive cross-reactivity of antigens on tumour cells with normal alloantigens present in the stimulating pool.Entities:
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Year: 1978 PMID： 74499 DOI： 10.1016/s0140-6736(78)90364-1
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321