Literature DB >> 74498

Polyamine interaction with pregnancy serum in suppression of lymphocyte transformation.

J M Gaugas, P Curzen.   

Abstract

Biogenic polyamines interacting with pregnancy serum elicit potent suppression of lymphocyte transformation in vitro. Within the assay limits, activity was first shown after about 15 weeks' gestation and reached its highest level at about 28 weeks. This level was maintained until term. It is thought that specific humoral amine oxidases were the cause. Fetal-cord serum and non-pregnancy serum were inactive. This system may have an immunoregulatory function in pregnancy.

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Year:  1978        PMID： 74498     DOI： 10.1016/s0140-6736(78)90363-x

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  14 in total

1.  Serum spermidine oxidase activity in patients with insulin-dependent diabetes mellitus and microvascular complications.

Authors:  G Seghieri; A Gironi; M Niccolai; P Mammini; L Alviggi; L A De Giorgio; P Caselli; G Bartolomei
Journal:  Acta Diabetol Lat       Date:  1990 Oct-Dec

2.  Oxidized polyamines and the growth of human vascular endothelial cells. Prevention of cytotoxic effects by selective acetylation.

Authors:  D M Morgan
Journal:  Biochem J       Date:  1987-03-01       Impact factor: 3.857

3.  Inhibition of lymphocyte growth by spermidine in medium containing fetal bovine serum.

Authors:  T L Swanson; G E Gibbs
Journal:  In Vitro       Date:  1980-09

4.  A comparison between the composition of maternal peripheral plasma and plasma collected from the retroplacental compartment at caesarean section. A study on protein and steroid hormones and binding proteins.

Authors:  M Norman; C G Eriksson; P Eneroth
Journal:  Arch Gynecol Obstet       Date:  1989       Impact factor: 2.344

5.  Anti-inflammatory effects of polyamines in serotonin and carrageenan paw edemata - possible mechanism to increase vascular permeability inhibitory protein level which is regulated by glucocorticoids and superoxide radical.

Authors:  Y Oyanagui
Journal:  Agents Actions       Date:  1984-02

6.  Inactivation of human immunodeficiency virus type 1 by the amine oxidase-peroxidase system.

Authors:  S J Klebanoff; F Kazazi
Journal:  J Clin Microbiol       Date:  1995-08       Impact factor: 5.948

7.  Spermidine cytotoxicity in vitro: effect of serum and oxygen tension.

Authors:  O D Hegre; S Marshall; G E Hickey
Journal:  In Vitro       Date:  1984-03

8.  Effects of prostaglandins E2 and I2 on human lymphocyte transformation in the presence and absence of inhibitors of prostaglandin biosynthesis.

Authors:  D Gordon; D C Henderson; J Westwick
Journal:  Br J Pharmacol       Date:  1979-09       Impact factor: 8.739

9.  Polyamine-polyamine oxidase interaction: part of maternal protective mechanism against fetal rejection.

Authors:  D M Morgan; G Illei
Journal:  Br Med J       Date:  1980-05-31

10.  Spermidine oxidase in human pregnancy serum. Probable identity with diamine oxidase.

Authors:  W A Gahl; A M Vale; H C Pitot
Journal:  Biochem J       Date:  1982-01-01       Impact factor: 3.857
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