Literature DB >> 7448431

[Culture of mononuclear cells from patients with aplastic anemia in diffusion chambers (author's transl)].

L Böning, B Lau, W Wilmanns.   

Abstract

The growth of mononuclear human peripheral blood cells from five patients with aplastic anemia (AA) was tested in diffusion chambers over a period of 13 days. Considerable differences were seen in the total cell number compared with controls. The total cell number of three patients with AA was markedly lower than in the control group (eight controls). The differentiation of the cells showed considerable differences in the growth patterns of the lymphocytes and in granulopoiesis; in three of five patients with AA no granulopoiesis was observed.

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Year:  1980        PMID: 7448431     DOI: 10.1007/bf01007769

Source DB:  PubMed          Journal:  Blut        ISSN: 0006-5242


  16 in total

1.  The growth of human bone marrow in diffusion chambers.

Authors:  D J Squires
Journal:  Br J Haematol       Date:  1975-01       Impact factor: 6.998

2.  [Culture of leukocytes of patients with hairy cell leukaemia in the diffusion chamber (author's transl)].

Authors:  F J Tigges; H W Heyden; H D Waller
Journal:  Blut       Date:  1977-08-29

3.  Editorial: The pathogenesis of aplastic anemia: a defective pluripotent hematopoietic stem cell with inappropriate balance of differentiation and self-replication.

Authors:  D R Boggs; S S Boggs
Journal:  Blood       Date:  1976-07       Impact factor: 22.113

4.  Granulocytic colony forming cells in vitro: II. Patients with aplastic anaemia.

Authors:  P Kern; W Heit; B Kubanek; H Heimpel
Journal:  Blut       Date:  1977-05

5.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

6.  Formation of granulocytes and macrophages in diffusion chamber cultures of mouse blood leucocytes.

Authors:  H B Benestad
Journal:  Scand J Haematol       Date:  1970

7.  In vitro granulocytic colony-forming potential of bone marrow from patients with granulocytopenia and aplastic anemia.

Authors:  J E Kurnick; W A Robinson; C A Dickey
Journal:  Proc Soc Exp Biol Med       Date:  1971-07

8.  Aplastic anemia--suppressor lymphocytes and hematopoiesis.

Authors:  R A Good
Journal:  N Engl J Med       Date:  1977-01-06       Impact factor: 91.245

9.  Bone-marrow microenvironment defect in congenital hypoplastic anemia.

Authors:  W B Ershler; J Ross; J L Finlay; N T Shahidi
Journal:  N Engl J Med       Date:  1980-06-12       Impact factor: 91.245

Review 10.  Recent developments in understanding the pathogenesis of aplastic anemia.

Authors:  J H Fitchen; M J Cline
Journal:  Am J Hematol       Date:  1978       Impact factor: 10.047

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