Literature DB >> 7448347

Pharmacokinetic characteristics of two different formulations of trimipramine determined with a new GLC method.

G Caillé, J G Besner, Y Lacasse, M Vézina.   

Abstract

A sensitive and specific gas chromatographic method using a nitrogen detector for the measurement of trimipramine plasma concentrations is described. This method was used to determine the relative bioavailability and some pharmacokinetic parameters of two formulations, tablets and capsules, in healthy volunteers. It was concluded the tablet and capsule formulations were pharmacokinetically equivalent.

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Year:  1980        PMID: 7448347     DOI: 10.1002/bdd.2510010406

Source DB:  PubMed          Journal:  Biopharm Drug Dispos        ISSN: 0142-2782            Impact factor:   1.627


  3 in total

1.  Bioavailability prediction based on molecular structure for a diverse series of drugs.

Authors:  Joseph V Turner; Desmond J Maddalena; Snezana Agatonovic-Kustrin
Journal:  Pharm Res       Date:  2004-01       Impact factor: 4.200

2.  Chronopharmacokinetic and bioequivalence studies of two formulations of trimipramine after oral administration in man.

Authors:  A M Bougerolle; J L Chabard; M Jbilou; G Dordain; A Eschalier; O Aumaitre; J Gaillot; J J Piron; J Petit; J A Berger
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1989 Apr-Jun       Impact factor: 2.441

Review 3.  Clinical originality and new biology of trimipramine.

Authors:  M Gastpar
Journal:  Drugs       Date:  1989       Impact factor: 9.546

  3 in total

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