Literature DB >> 7447411

Comparative nephrotoxicities of high-dose netilmicin and tobramycin in rats.

R A Parker, D N Gilbert, D C Houghton, G A Porter, W M Bennett.   

Abstract

The nephrotoxic potentials of netilmicin and tobramycin given in doses of 180 mg/kg per day for up to 14 days were compared in Fischer rats. At this dosage, tobramycin produced mortality and significant changes in renal structure and function; netilmicin evoked minimal nephrotoxicity.

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Year:  1980        PMID： 7447411      PMCID： PMC283993          DOI： 10.1128/AAC.18.2.346

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  Renal transport of organic acids and bases in aminoglycoside nephrotoxicity.

Authors:  W M Bennett; C E Plamp; R A Parker; D N Gilbert; D C Houghton; G A Porter
Journal:  Antimicrob Agents Chemother       Date:  1979-08       Impact factor: 5.191

2.  Specificity of the inhibitory effect of "uremic" serum on p-aminohippurate transport.

Authors:  J B Hook; J R Munro
Journal:  Proc Soc Exp Biol Med       Date:  1968-01

3.  Composition and function of rat kidneys after transient normothermic ischemia.

Authors:  R Keeler
Journal:  Can J Physiol Pharmacol       Date:  1968-09       Impact factor: 2.273

4.  Comparative nephrotoxicities of gentamicin, netilmicin and tobramycin in the rat.

Authors:  L Soberon; R L Bowman; E Pastoriza-Munoz; G J Kaloyanides
Journal:  J Pharmacol Exp Ther       Date:  1979-09       Impact factor: 4.030

5.  Comparison of the nephrotoxicity of netilmicin and gentamicin in rats.

Authors:  R L Bowman; F J Silverblatt; G J Kaloyanides
Journal:  Antimicrob Agents Chemother       Date:  1977-10       Impact factor: 5.191

6.  Comparative nephrotoxicities of netilmicin and gentamicin in rats.

Authors:  F C Luft; M N Yum; S A Kleit
Journal:  Antimicrob Agents Chemother       Date:  1976-11       Impact factor: 5.191

7.  Comparative nephrotoxicity of gentamicin and tobramycin in rats.

Authors:  D N Gilbert; C Plamp; P Starr; W M Bennet; D C Houghton; G Porter
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

8.  Comparative nephrotoxicity of aminoglycoside antibiotics in rats.

Authors:  F C Luft; R Bloch; R S Sloan; M N Yum; R Costello; D R Maxwell
Journal:  J Infect Dis       Date:  1978-10       Impact factor: 5.226
  8 in total
  6 in total

1.  Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides.

Authors:  M El Mouedden; G Laurent; M P Mingeot-Leclercq; H S Taper; J Cumps; P M Tulkens
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

Review 2.  Aminoglycoside research 1975-1985: prospects for development of improved agents.

Authors:  K E Price
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

3.  Univariate and multivariate analyses of risk factors predisposing to auditory toxicity in patients receiving aminoglycosides.

Authors:  J M Gatell; F Ferran; V Araujo; M Bonet; E Soriano; J Traserra; J G SanMiguel
Journal:  Antimicrob Agents Chemother       Date:  1987-09       Impact factor: 5.191

4.  Nonparallel nephrotoxicity dose-response curves of aminoglycosides.

Authors:  G H Hottendorf; D Barnett; L L Gordon; E F Christensen; H Madissoo
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191

5.  Single-dose accumulation pharmacokinetics of tobramycin and netilmicin in normal volunteers.

Authors:  N E Winslade; M H Adelman; E J Evans; J J Schentag
Journal:  Antimicrob Agents Chemother       Date:  1987-04       Impact factor: 5.191

6.  Prospective randomized double-blind comparison of nephrotoxicity and auditory toxicity of tobramycin and netilmicin.

Authors:  J M Gatell; J G SanMiguel; V Araujo; L Zamora; J Maña; M Ferrer; M Bonet; M Bohe; M T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1984-11       Impact factor: 5.191
  6 in total

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