Literature DB >> 7445978

Polysaccharide accumulation in the central nervous system of D-penicillamine-treated rats.

A P Jayaraj.   

Abstract

A complex polysaccharide accumulation was observed in the central nervous system (CNS) of rats treated with D-penicillamine similar to Lafora-like bodies. They have histochemical similarities comparable to bodies described in previous studies of Lafora disease. The clinical usefulness of D-penicillamine has been limited by many side effects including renal damage. It is suggested that, in addition to D-penicillamine nephropathy, there are toxic effects of this drug on the CNS.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7445978     DOI： 10.1007/bf00687391

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  13 in total

1.  Penicillamine, a new oral therapy for Wilson's disease.

Authors:  J M WALSHE
Journal:  Am J Med       Date:  1956-10       Impact factor: 4.965

2.  Progressive familial myoclonic epilepsy in three families: its clinical features and pathological basis.

Authors:  D G HARRIMAN; J H MILLAR; A C STEVENSON
Journal:  Brain       Date:  1955-09       Impact factor: 13.501

3.  Intra-axonal Corpora amylacea in ventral and lateral horns of the spinal cord.

Authors:  K Takahashi; M Agari; H Nakamura
Journal:  Acta Neuropathol       Date:  1975       Impact factor: 17.088

4.  Specific therapy for rheumatoid arthritis.

Authors:  E C Huskisson
Journal:  Rheumatol Rehabil       Date:  1976-08

5.  Effect of penicillamine on human collagen and its possible application to treatment of scleroderma.

Authors:  E D Harris; A Sjoerdsma
Journal:  Lancet       Date:  1966-11-05       Impact factor: 79.321

6.  Controlled trial of D(-)penicillamine in severe rheumatoid arthritis.

Authors: 
Journal:  Lancet       Date:  1973-02-10       Impact factor: 79.321

7.  Presenile dementia with "Lafora-like" intraneuronal inclusions.

Authors:  K Suzuki; E David; B Kutschman
Journal:  Arch Neurol       Date:  1971-07

8.  Nephropathy induced by D-penicillamine.

Authors:  I A Jaffe; G Treser; Y Suzuki; T Ehrenreich
Journal:  Ann Intern Med       Date:  1968-09       Impact factor: 25.391

9.  A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. I. Metabolic and functional abnormalities in soft tissues.

Authors:  M E Nimni
Journal:  J Biol Chem       Date:  1968-04-10       Impact factor: 5.157

10.  Desmosine biosynthesis: nature of inhibition by D-penicillamine.

Authors:  S R Pinnell; G R Martin; E J Miller
Journal:  Science       Date:  1968-08-02       Impact factor: 47.728
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.