Literature DB >> 7443601

Severe barbiturate and paracetamol overdose: the simultaneous removal of both poisons by haemoperfusion.

M Helliwell.   

Abstract

Charcoal haemoperfusion was successful in the treatment of severe butobarbitone poisoning complicated by resistant hypotension. At the same time the rapid removal of paracetamol may have lessened the severity of the subsequent hepatic injury. The mechanism and management of shock associated with barbiturate poisoning, and the possible application of haemoperfusion in paracetamol poisoning are discussed.

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Year:  1980        PMID： 7443601      PMCID： PMC2425606          DOI： 10.1136/pgmj.56.655.363

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  13 in total

1.  THE MECHANISM OF SHOCK FOLLOWING SUICIDAL DOSES OF BARBITURATES, NARCOTICS AND TRANQUILIZER DRUGS, WITH OBSERVATIONS ON THE EFFECTS OF TREATMENT.

Authors:  H SHUBIN; M H WEIL
Journal:  Am J Med       Date:  1965-06       Impact factor: 4.965

2.  Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.

Authors:  B G Gazzard; B Widdop; M Davis; R D Hughes; R Goulding; R Williams
Journal:  Postgrad Med J       Date:  1977-05       Impact factor: 2.401

3.  Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage.

Authors:  L F Prescott; P Roscoe; N Wright; S S Brown
Journal:  Lancet       Date:  1971-03-13       Impact factor: 79.321

4.  Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.

Authors:  N Wrights; L F Prescott
Journal:  Scott Med J       Date:  1973-03       Impact factor: 0.729

5.  Recent advances in the pharmacology of catecholamines.

Authors:  L I Goldberg
Journal:  Intensive Care Med       Date:  1977-12       Impact factor: 17.440

6.  Use of charcoal haemoperfusion in the management of severely poisoned patients.

Authors:  J A Vale; A J Rees; B Widdop; R Goulding
Journal:  Br Med J       Date:  1975-01-04

7.  Experimental drug intoxication: treatment with charcoal haemoperfusion.

Authors:  B Widdop; R K Medd; R A Braithwaite; A J Rees; R Goulding
Journal:  Arch Toxicol       Date:  1975-09-05       Impact factor: 5.153

8.  Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning.

Authors:  A P Douglas; A N Hamlyn; O James
Journal:  Lancet       Date:  1976-01-17       Impact factor: 79.321

9.  Oral methionine in the treatment of severe paracetamol (Acetaminophen) overdose.

Authors:  P Crome; J A Vale; G N Volans; B Widdop; R Goulding
Journal:  Lancet       Date:  1976-10-16       Impact factor: 79.321

10.  Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine.

Authors:  L F Prescott; J Park; A Ballantyne; P Adriaenssens; A T Proudfoot
Journal:  Lancet       Date:  1977-08-27       Impact factor: 79.321
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  2 in total

Review 1.  Paracetamol overdosage. Pharmacological considerations and clinical management.

Authors:  L F Prescott
Journal:  Drugs       Date:  1983-03       Impact factor: 9.546

2.  Paracetamol metabolites in the neonate following maternal overdose.

Authors:  I Roberts; M J Robinson; M Z Mughal; J G Ratcliffe; L F Prescott
Journal:  Br J Clin Pharmacol       Date:  1984-08       Impact factor: 4.335
  2 in total

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