Literature DB >> 744236

Synthesis of some 11H-indolo[3,2-c][1,8]naphthyridines.

A Da Settimo, G Biagi, G Primofiore, P L Ferrarini, O Livi.   

Abstract

The preparation of some 11H-indolo[3,2-c] [1,8]naphthyridines (V), having oxygen functions at positions 3 or 3 and 10 or 3 and 8, as in steroidal active compounds, is described. Compounds (V) were obtained using the Fisher indole synthesis. The preparation of the parent nucleus: 11H-indolo [3,2-c] [1,8]naphthyridines (V n) is also described. Some compounds were subjected to pharmacological screening, but none was found to be significantly active.

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Year:  1978        PMID: 744236

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  1 in total

1.  Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels-Alder reactions.

Authors:  Salah Fadel; Youssef Hajbi; Mostafa Khouili; Said Lazar; Franck Suzenet; Gérald Guillaumet
Journal:  Beilstein J Org Chem       Date:  2014-01-28       Impact factor: 2.883

  1 in total

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