Literature DB >> 7442267

A simplified method for assessing drug effects on gastric emptying in rats.

D A Droppleman, R L Gregory, R S Alphin.   

Abstract

A method is described to determine the effects of experimental compounds on gastric emptying in rats. The technique, using a methylcellulose-based test meal, is simple, versatile and reliable. Data are presented to show the utility of the method in demonstrating both enhancement and inhibition of gastric emptying.

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Year:  1980        PMID: 7442267     DOI: 10.1016/0160-5402(80)90014-5

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN: 0160-5402


  4 in total

1.  5-HT4 receptor mediated stimulation of gastric emptying in rats.

Authors:  S S Hegde; A G Wong; M R Perry; P Ku; T M Moy; M Loeb; R M Eglen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-06       Impact factor: 3.000

2.  Exploring new pharmacology and toxicological screening and safety evaluation of one widely used formulation of Nidrakar Bati from South Asia region.

Authors:  Afria Zaman; Md Shamsuddin Sultan Khan; Lucky Akter; Sharif Hossain Syeed; Jakia Akter; Abdullah Al Mamun; Md Ershad Alam; Md Ahsan Habib; Md Abdul Jalil
Journal:  BMC Complement Altern Med       Date:  2015-04-16       Impact factor: 3.659

3.  Antagonism of cisplatin-induced emesis by metoclopramide and dazopride through enhancement of gastric motility.

Authors:  R S Alphin; A G Proakis; C A Leonard; W L Smith; W N Dannenburg; W J Kinnier; D N Johnson; L F Sancilio; J W Ward
Journal:  Dig Dis Sci       Date:  1986-05       Impact factor: 3.199

4.  Validation of octanoate breath test for measuring gastric emptying in rats.

Authors:  Ingrid Demedts; Christophe Vanormelingen; Hubert Van Billoen; Tim Vanuytsel; Ricard Farré; Tatsuhiro Masaoka; Alfons Verbruggen; Kristien Verbeke; Pieter Vanden Berghe; Jan Tack
Journal:  J Neurogastroenterol Motil       Date:  2013-04-16       Impact factor: 4.924

  4 in total

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