Literature DB >> 7441112

A method for the evaluation of dose-effect data utilizing a programmable calculator.

E L Carmines, R A Carchman, J F Borzelleca.   

Abstract

A program for the calculation of the median effective dose (ED50) and the slope of the dose-effect line was developed for a programmable calculator. The method employed approximated the solution described by Bliss. Experimental data were evaluated and compared to both hand calculated results and results of other computer methods. This method produced results which differed from other computer methods by less than 1 percent. This program provided information necessary for the test for parallelism and estimate of relative potency of two dose-effect lines.

Mesh:

Year:  1980        PMID: 7441112

Source DB:  PubMed          Journal:  J Environ Pathol Toxicol        ISSN: 0146-4779


  3 in total

1.  Comparison of subarachnoid anesthetic effect of emulsified volatile anesthetics in rats.

Authors:  Jiao Guo; Cheng Zhou; Peng Liang; Han Huang; Fengshan Li; Xiangdong Chen; Jin Liu
Journal:  Int J Clin Exp Pathol       Date:  2014-12-01

2.  Neuropharmacology of a new potential anxiolytic compound, F 2692, 1-(3'-trifluoromethyl phenyl) 1,4-dihydro 3-amino 4-oxo 6-methyl pyridazine. 1. Acute and in vitro effects.

Authors:  M B Assié; P Chopin; A Stenger; C Palmier; M Briley
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

3.  Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures.

Authors:  G Eadon; L Kaminsky; J Silkworth; K Aldous; D Hilker; P O'Keefe; R Smith; J Gierthy; J Hawley; N Kim
Journal:  Environ Health Perspect       Date:  1986-12       Impact factor: 9.031

  3 in total

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