| Literature DB >> 7439679 |
Abstract
Some generalized two-locus, major-gene models for traits exhibiting continuous expression are investigated. Conditions of gametic equilibria are stated as functions of the parameters characterizing the within phenotypic-genotypic distributions. Selection is stabilizing in favor of an optimum phenotype. It is established that an increase in the phenotypic variance facilitates stability of a central polymorphic state with tighter linkage. Also, with increased phenotypic variance in an additive two-locus selection model, a HARDY-WEINBERG type of equilibrium will be less central. The rate of convergence, in this case, is slowed down with an augmented environmental background.Mesh:
Year: 1980 PMID: 7439679 PMCID: PMC1214176
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562