Literature DB >> 7438960

Hydralazine-induced liver injury.

S Itoh, Y Yamaba, A Ichinoe, Y Tsukada.   

Abstract

A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies revealed that this liver injury was induced by hydralazine.

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Year:  1980        PMID： 7438960     DOI： 10.1007/bf01338533

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  5 in total

Review 1.  Medical intelligence drug therapy.

Authors:  J Koch-Weser
Journal:  N Engl J Med       Date:  1976-08-05       Impact factor: 91.245

2.  Hydralazine disease associated with transient granulomas in the liver. A case report.

Authors:  G P Jori; C Peschile
Journal:  Gastroenterology       Date:  1973-06       Impact factor: 22.682

3.  [Dihydralazine-induced acute hepatitis with IgM deficiency].

Authors:  M Knoblauch; B Cueni; M Spycher; M Schmid
Journal:  Schweiz Med Wochenschr       Date:  1977-05-14

4.  [Liver damage caused by adelphan].

Authors:  R Enat; G Rader; D Barzilai
Journal:  Schweiz Med Wochenschr       Date:  1977-05-14

5.  Acetylator phenotype in patients with hydralazine-induced lupoid syndrome.

Authors:  I Strandberg; G Boman; L Hassler; F Sjöqvist
Journal:  Acta Med Scand       Date:  1976
  5 in total
  1 in total

Review 1.  Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases.

Authors:  J Ludwig; R Axelsen
Journal:  Dig Dis Sci       Date:  1983-07       Impact factor: 3.199
  1 in total

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