| Literature DB >> 7438556 |
R W Pitcher-Wilmott, P Hindocha, C B Wood.
Abstract
Total IgG concentrations and the concentrations of the four subclasses of IgG were estimated in thirty-four pairs of maternal and foetal sera from pregnancies of various gestations ranging from 28 to 42 weeks using the method of radial immunodiffusion. It was found that: (1) all subclasses of IgG cross the human placenta freely, (2) foetal levels of IgG and each subclass of IgG exceed maternal levels in full-term pregnancies and (3) there was a close linear relationship between gestational age and the placental transfer of IgG and each of its subclasses.Entities:
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Year: 1980 PMID： 7438556 PMCID： PMC1537014
Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330