Literature DB >> 7438075

An in vitro assay procedure to test chemotherapeutic drugs on cells from human solid tumors.

S Shrivastav, R A Bonar, K R Stone, D F Paulson.   

Abstract

An in vitro assay was developed to measure the chemotherapeutic drug susceptibility of cells from human tumors. The assay utilized live cells, freshly isolated from tumor tissue, which were incubated for a short period in vitro. The drug-induced inhibition of incorporation of radiolabeled precursor into DNA, RNA, and protein was measured. The assay is sensitive to concentrations of chemotherapeutic drugs in the therapeutic range and is reproducible when tested with replicates of the same tumor cell population.

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Year:  1980        PMID： 7438075

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  9 in total

1.  Prostatic epithelium inhibiting factor (PEIF): organ specificity and production by prostatic fibroblasts.

Authors:  J J König; J C Romijn; F H Schröder
Journal:  Urol Res       Date:  1987

2.  A trial of the in vitro sensitivity test of anti-cancer drugs using primary cultured urogenital cancer cells.

Authors:  T Miura; Y Kubota; T Sakuramoto; M Hosaka
Journal:  Urol Res       Date:  1987

Review 3.  Resistance to cisplatin and analogues: mechanisms and potential clinical implications.

Authors:  A de Graeff; R J Slebos; S Rodenhuis
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

Review 4.  The efficacy of 9-cis retinoic acid in experimental models of cancer.

Authors:  M M Gottardis; W W Lamph; D R Shalinsky; A Wellstein; R A Heyman
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

5.  Ex vivo hemodialysis culture system for assessing the activity of cancer chemotherapeutic agents.

Authors:  J M Quarles; N G Morris; A Leibovitz
Journal:  In Vitro       Date:  1982-02

6.  Comparative study of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and tritiated thymidine in a chemosensitivity test using collagen gel matrix.

Authors:  M Egawa; H Hisazumi; T Uchibayashi; M Tanaka; T Sasaki
Journal:  Urol Res       Date:  1993-03

7.  Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.

Authors:  J G van Oosterwijk; M A J H van Ruler; I H Briaire-de Bruijn; B Herpers; H Gelderblom; B van de Water; J V M G Bovée
Journal:  Br J Cancer       Date:  2013-08-06       Impact factor: 7.640

8.  A comparison of three assays used for the in vitro chemosensitivity testing of human tumours.

Authors:  A P Wilson; C H Ford; C E Newman; A Howell
Journal:  Br J Cancer       Date:  1984-01       Impact factor: 7.640

9.  Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy.

Authors:  Marieke A de Graaff; Marije A J de Rooij; Brendy E W M van den Akker; Hans Gelderblom; Fréderic Chibon; Jean-Michel Coindre; Adrian Marino-Enriquez; Jonathan A Fletcher; Anne-Marie Cleton-Jansen; Judith V M G Bovée
Journal:  Br J Cancer       Date:  2016-05-03       Impact factor: 7.640
  9 in total

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