Literature DB >> 7437457

Phospholipid-transfer activity in type II cells isolated from adult rat lung.

M Post, J J Batenburg, E A Schuurmans, L M van Golde.   

Abstract

The soluble fraction from adult rat lung type II cells stimulated the transfer of various phospholipids between either liposomes or rat lung microsomes and rat lung mitochondria. Compared to whole lung, type II cells are highly enriched in transfer activity suggesting that phospholipid-transfer proteins play a role in the transport of surfactant phospholipids. Sephadex chromatography of pH 5.1 supernatant from type II cells yielded only one fraction catalysing the transfer of phosphatidylcholine, phosphatidylglycerol and phosphatidylethanolamine, while chromatography of pH 5.1 supernatant from whole lung yielded in addition a specific phosphatidylcholine-transfer and a specific phosphatidylglycerol-transfer protein.

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Year:  1980        PMID: 7437457     DOI: 10.1016/0005-2760(80)90212-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  4 in total

1.  Phosphatidylserine translocation to the mitochondrion is an ATP-dependent process in permeabilized animal cells.

Authors:  D R Voelker
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

2.  Phospholipid-transfer activities in cytosols from lung, isolated alveolar type II cells and alveolar type II cell-derived adenomas.

Authors:  G L Pool; D G Bubacz; R H Lumb; R J Mason
Journal:  Biochem J       Date:  1983-12-01       Impact factor: 3.857

3.  Phospholipid-transfer proteins and their mRNAs in developing rat lung and in alveolar type-II cells.

Authors:  J J Batenburg; B C Ossendorp; G T Snoek; K W Wirtz; M Houweling; R H Elfring
Journal:  Biochem J       Date:  1994-02-15       Impact factor: 3.857

Review 4.  Lung surfactant.

Authors:  S A Rooney
Journal:  Environ Health Perspect       Date:  1984-04       Impact factor: 9.031

  4 in total

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