Literature DB >> 7437451

The possible antiketogenic and gluconeogenic effect of the omega-oxidation of fatty acids in rats.

P B Mortensen.   

Abstract

The urinary excretion of C4--C10-dicarboxylic acids and 3-hydroxybutyric acid was examined in rats on ketogenic stimulation due to fat-feeding. The urinary excretion of succinic acid decreased while the urinary excretion of adipic and suberic acids increased prior to the appearance of ketosis, and this pattern of excretion was almost independent of the degree of the subsequent ketosis. After administering adipic acid to the ketotic rats, urinary excretion of succinic acid increased at the same time as ketosis decreased and blood glucose increased. The possibility of a physiological antiketogenic and gluconeogenic effect of the omega-oxidation of fatty acids to dicarboxylic acids is discussed.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7437451     DOI： 10.1016/0005-2760(80)90199-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.

Authors:  Sivakama S Bharathi; Yuxun Zhang; Zhenwei Gong; Radhika Muzumdar; Eric S Goetzman
Journal:  Biochem Biophys Res Commun       Date:  2020-04-29       Impact factor: 3.575

Review 2.  The inborn errors of mitochondrial fatty acid oxidation.

Authors:  C Vianey-Liaud; P Divry; N Gregersen; M Mathieu
Journal:  J Inherit Metab Dis       Date:  1987       Impact factor: 4.982

3.  Metabolite profiling identifies markers of uremia.

Authors:  Eugene P Rhee; Amanda Souza; Laurie Farrell; Martin R Pollak; Gregory D Lewis; David J R Steele; Ravi Thadhani; Clary B Clish; Anna Greka; Robert E Gerszten
Journal:  J Am Soc Nephrol       Date:  2010-04-08       Impact factor: 10.121

4.  Gas chromatography--mass spectrometry (GC--MS) diagnosis of two cases of medium chain acyl-CoA dehydrogenase deficiency.

Authors:  P Divry; C Vianey-Liaud; J Cotte
Journal:  J Inherit Metab Dis       Date:  1984       Impact factor: 4.982

Review 5.  The Mystery of Extramitochondrial Proteins Lysine Succinylation.

Authors:  Christos Chinopoulos
Journal:  Int J Mol Sci       Date:  2021-06-04       Impact factor: 5.923

6.  Effect of a fat spread enriched with medium-chain triacylglycerols and a special fatty acid-micronutrient combination on cardiometabolic risk factors in overweight patients with diabetes.

Authors:  Roswitha Siener; Christina Ehrhardt; Norman Bitterlich; Christine Metzner
Journal:  Nutr Metab (Lond)       Date:  2011-04-08       Impact factor: 4.169

Review 7.  The biological significance of ω-oxidation of fatty acids.

Authors:  Yoshiro Miura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2013       Impact factor: 3.493

8.  Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation.

Authors:  Marta G Novelle; Susana Belén Bravo; Maxime Deshons; Cristina Iglesias; María García-Vence; Rebecca Annells; Natália da Silva Lima; Rubén Nogueiras; Manuel Alejandro Fernández-Rojo; Carlos Diéguez; Amparo Romero-Picó
Journal:  iScience       Date:  2021-01-19

9.  Association between maternal exposure to phthalates and lower language ability in offspring derived from hair metabolome analysis.

Authors:  Beatrix Jones; Ting-Li Han; Thibaut Delplancke; Elizabeth J McKenzie; Jamie V de Seymour; Mei Chien Chua; Kok Hian Tan; Philip N Baker
Journal:  Sci Rep       Date:  2018-04-30       Impact factor: 4.379
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.