Growth retardation of weddellite (calcium oxalate dihydrate) by sodium copper chlorophyllin.

We studied the growth of calcium oxalate dihydrate crystals (weddellite) in simulated urine and its transformation into the more stable monohydrate (whewellite). Sodium copper chlorophyllin in a concentration of 100 microgram per ml inhibited the growth of calcium oxalate dihydrate crystals in simulated urine. The size distribution parameters of the dihydrate crystals in the presence and absence of chlorophyllin suggest that soluble chlorophyllin could be of clinical significance in calcium oxalate urolithiasis.