Literature DB >> 7437040

Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reacion with DNA.

Y Hashimoto, K Shudo, T Okamoto.   

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Year:  1980        PMID: 7437040     DOI: 10.1016/0006-291x(80)91222-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


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  6 in total

1.  Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2'-deoxyguanosine and its phosphate esters.

Authors:  H Nagaoka; K Wakabayashi; S B Kim; I S Kim; Y Tanaka; M Ochiai; A Tada; H Nukaya; T Sugimura; M Nagao
Journal:  Jpn J Cancer Res       Date:  1992-10

2.  Generation of intracellular active oxygens in mouse FM3A cells by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole, the activated Trp-P-2.

Authors:  Y Wataya; K Yamane; K Hiramoto; Y Ohtsuka; Y Okubata; K Negishi; H Hayatsu
Journal:  Jpn J Cancer Res       Date:  1988-05

Review 3.  Past, present, and future of mutagens in cooked foods.

Authors:  T Sugimura
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

4.  Metabolic aspects of pyrolysis mutagens in food.

Authors:  S Sato; C Negishi; A Umemoto; T Sugimura
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

5.  Chemical modification of DNA with muta-carcinogens. I. 3-Amino-1-methyl-5H-pyrido[4,3-b]indole and 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole: metabolic activation and structure of the DNA adducts.

Authors:  Y Hashimoto; K Shudo
Journal:  Environ Health Perspect       Date:  1985-10       Impact factor: 9.031

6.  Induction of DNA recombination by activated 3-amino-1-methyl-5H-pyrido[4,3-b]indole.

Authors:  K Hiramoto; S Kanamitsu; K Negishi; H Ikeda; H Hayatsu
Journal:  Jpn J Cancer Res       Date:  1995-02
  6 in total

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