Literature DB >> 7436546

2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of Seveso, Italy.

R Fanelli, M P Bertoni, M G Castelli, C Chiabrando, G P Martelli, A Noseda, S Garattini, C Binaghi, V Marazza, F Pezza.   

Abstract

After the environmental contamination by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the area of Seveso, Italy, thousands of small domestic animals (mainly rabbits and poultry) died within a few weeks. Autopsies on dead animals showed various pathological signs, such as hepatic lesions and haemorrhage. TCDD was monitored in animal tissues by gas chromatography-mass fragmentography; rabbit liver levels corresponded fairly well to soil contamination, which indicated that this species can be used as a tool for tracking the presence of TCDD in the environment.

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Year:  1980        PMID： 7436546     DOI： 10.1007/bf01056936

Source DB:  PubMed          Journal:  Arch Environ Contam Toxicol        ISSN： 0090-4341            Impact factor:   2.804


  12 in total

1.  Retention and excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rats.

Authors:  G F Fries; G S Marrow
Journal:  J Agric Food Chem       Date:  1975 Mar-Apr       Impact factor: 5.279

2.  TETRACHLORODIBENZO-p-DIOXIN RELEASE AT SÉVESO.

Authors:  A M Hay
Journal:  Disasters       Date:  1977-12

3.  TCDD poisoning at Seveso.

Authors:  S Garattini
Journal:  Biomedicine       Date:  1977-02

4.  The toxicity of polychlorinated polycyclic compounds and related chemicals.

Authors:  R D Kimbrough
Journal:  CRC Crit Rev Toxicol       Date:  1974-01

5.  Routine analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin in biological samples from the contaminated area of Seveso, Italy.

Authors:  R Fanelli; M P Bertoni; M Bonfanti; M G Castelli; C Chiabrando; G P Martelli; M A Noè; A Noseda; C Sbarra
Journal:  Bull Environ Contam Toxicol       Date:  1980-06       Impact factor: 2.151

6.  Studies of the chick edema disease. 9. Response of chicks fed or singly administered synthetic edema-producing compounds.

Authors:  D F Flick; D Firestone; G R Higginbotham
Journal:  Poult Sci       Date:  1972-11       Impact factor: 3.352

7.  Studies of the chick edema disease. 10. Toxicity of chick edema factors in the chick, chick embryo, and monkey.

Authors:  D F Flick; D Firestone; J Ress; J R Allen
Journal:  Poult Sci       Date:  1973-07       Impact factor: 3.352

8.  General biological effects of TCDD in laboratory animals.

Authors:  M W Harris; J A Moore; J G Vos; B N Gupta
Journal:  Environ Health Perspect       Date:  1973-09       Impact factor: 9.031

9.  A survey of the embryotoxic effects of TCDD in mammalian species.

Authors:  D Neubert; P Zens; A Rothenwallner; H J Merker
Journal:  Environ Health Perspect       Date:  1973-09       Impact factor: 9.031

10.  Toxicology of chlorinated dibenzo-p-dioxins.

Authors:  B A Schwetz; J M Norris; G L Sparschu; U K Rowe; P J Gehring; J L Emerson; C G Gerbig
Journal:  Environ Health Perspect       Date:  1973-09       Impact factor: 9.031
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  3 in total

Review 1.  The Seveso studies on early and long-term effects of dioxin exposure: a review.

Authors:  P A Bertazzi; I Bernucci; G Brambilla; D Consonni; A C Pesatori
Journal:  Environ Health Perspect       Date:  1998-04       Impact factor: 9.031

2.  Contamination of local wildlife following a fire at a polychlorinated biphenyls warehouse in St Basile le Grand, Quebec, Canada.

Authors:  D Phaneuf; J L DesGranges; N Plante; J Rodrigue
Journal:  Arch Environ Contam Toxicol       Date:  1995-02       Impact factor: 2.804

Review 3.  The use of mammals as sentinels for human exposure to toxic contaminants in the environment.

Authors:  D J O'Brien; J B Kaneene; R H Poppenga
Journal:  Environ Health Perspect       Date:  1993-03       Impact factor: 9.031
  3 in total

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