| Literature DB >> 74365 |
T Morito, K Tanimoto, Y Horiuchi, T Juji.
Abstract
Some anti-HLA sera showed Fc-rosette inhibitory activity, which had little correlation with type-specific anti-HLA activity. Cytotoxic titers did not correlate with Fc-rosette inhibition rate and these antisera showed considerable inhibition of rosette formation even after absorption of anti-HLA activity with T lymphocytes. These results suggest that some anti-HLA sera contain B-cell-specific inhibitory activity against Fc-receptor like anti-Ia antibody in mice. Rabbit antiserum against human beta2-microglobulin showed specific inhibition of Fc-rosette formation. It was suggested that Fc-receptor or Ia-like antigen in human has a close relation with beta2-microglobulin.Entities:
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Year: 1978 PMID： 74365 DOI： 10.1159/000232028
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN： 0020-5915