| Literature DB >> 7433983 |
J E Bakke, J A Gustafsson, B E Gustafsson.
Abstract
Three major metabolites of propachlor were isolated from the excreta of germfree rats given 14C-labeled propachlor orally. In contrast, 11 urinary metabolites, six of which were 2-methylsulfonylacetanilides not present in excreta of germfree rats, were isolated from control rats given 14C-labeled propachlor orally. Enterohepatic circulation and microbial metabolism in the intestine were necessary for production of the methylsulfonyl-containing and other metabolites of propachlor in the conventional rat.Entities:
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Year: 1980 PMID： 7433983 DOI： 10.1126/science.7433983
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728