Literature DB >> 7431123

The biological activity of 5,6-epoxyretinoic acid.

M H Zile, R C Inhorn, H F Deluca.   

Abstract

The potential of all-trans-5,6-epoxyretinoic acid to promote growth in vitamin A-deficient rats was evaluated over a 25-fold dose range using single daily intraperitoneal injections. 5,6-Epoxyretinoic acid was found to be 0.5% as active as all-trans-retinoic acid. The discrepancies between the present results and those obtained previously by other workers are discussed.

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Year:  1980        PMID: 7431123     DOI: 10.1093/jn/110.11.2225

Source DB:  PubMed          Journal:  J Nutr        ISSN: 0022-3166            Impact factor:   4.798


  3 in total

1.  Polymeric micelles of PEG-PE as carriers of all-trans retinoic acid for stability improvement.

Authors:  Angkana Wichit; Anothai Tangsumranjit; Tasana Pitaksuteepong; Neti Waranuch
Journal:  AAPS PharmSciTech       Date:  2012-01-25       Impact factor: 3.246

2.  Synthesis and metabolism of all-trans-[11-3H]retinyl beta-glucuronide in rats in vivo.

Authors:  A B Barua; R O Batres; J A Olson
Journal:  Biochem J       Date:  1988-06-01       Impact factor: 3.857

3.  The epithelial differentiating activity in vivo of (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl) -1-propenyl]benzoic acid and 4,4-difluororetinoic acid.

Authors:  D A Miller; A Stephens-Jarnagin; H F DeLuca
Journal:  Biochem J       Date:  1985-04-01       Impact factor: 3.857

  3 in total

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