Literature DB >> 7429992

Structure of CC-1065 (NSC-298223), a new antitumor antibiotic.

D G Martin, C G Chidester, D J Duchamp, S A Mizsak.   

Abstract

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Year:  1980        PMID： 7429992     DOI： 10.7164/antibiotics.33.902

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


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  13 in total

1.  Spectrum of cell-cycle kinetics of alkylating agent adolezesin in gynecological cancer cell lines: correlation with drug-induced cytotoxicity.

Authors:  H N Nguyen; B U Sevin; H Averette; J Perras; R Ramos; D Donato
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  In vitro evaluation of a novel chemotherapeutic agent, Adozelesin, in gynecologic-cancer cell lines.

Authors:  H N Nguyen; B U Sevin; H Averette; J Perras; R Hightower; R Ramos; D Donato; M Penalver
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065.

Authors:  D L Walker; J M Reid; M M Ames
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

4.  Phase I trial of Adozelesin using the treatment schedule of daily x5 every 3 weeks.

Authors:  B J Foster; P M LoRusso; E Poplin; M Zalupski; M Valdivieso; A Wozniak; L Flaherty; D A Kasunic; R H Earhart; L H Baker
Journal:  Invest New Drugs       Date:  1996       Impact factor: 3.850

5.  Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065.

Authors:  L H Li; R C Kelly; M A Warpehoski; J P McGovren; I Gebhard; T F DeKoning
Journal:  Invest New Drugs       Date:  1991-05       Impact factor: 3.850

6.  V79 Chinese hamster lung cells resistant to the bis-alkylator bizelesin are multidrug-resistant.

Authors:  R K Butryn; K S Smith; E G Adams; I Abraham; J Stackpole; K E Sampson; B K Bhuyan
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

7.  Adozelesin, a potent new alkylating agent: cell-killing kinetics and cell-cycle effects.

Authors:  B K Bhuyan; K S Smith; E G Adams; T L Wallace; D D Von Hoff; L H Li
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

8.  Synergistic and additive combinations of several antitumor drugs and other agents with the potent alkylating agent adozelesin.

Authors:  K S Smith; B A Folz; E G Adams; B K Bhuyan
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

9.  Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug.

Authors:  Yuqiang Wang; Huiling Yuan; Susan C Wright; Hong Wang; James W Larrick
Journal:  BMC Chem Biol       Date:  2001

10.  Synthesis and cytotoxicity of a biotinylated CC-1065 analogue.

Authors:  Yuqiang Wang; Huiling Yuan; Susan C Wright; Hong Wang; James W Larrick
Journal:  BMC Chem Biol       Date:  2002
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