Literature DB >> 7429919

Combined immunodeficiency of Arabian horses: confirmation of autosomal recessive mode of inheritance.

L E Perryman, R L Torbeck.   

Abstract

A 3-year prospective breeding trial was designed to verify the mode of inheritance of combined immunodeficiency (CID) in Arabian horses. Twenty-six mares that had previously produced foals with CID were mated to a stallion that had sired foals with CID. Of 53 foals obtained, 15 (28.3%) had CID. The ratio of female to male foals was 28:25, and the ratio of female CID to male CID foals was 8:7. The results of this trial confirmed a suggestion that CID in Arabian horses is inherited as an autosomal recessive trait.

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Year:  1980        PMID： 7429919

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN： 0003-1488            Impact factor:   1.936


  11 in total

1.  Protective effects of broadly neutralizing immunoglobulin against homologous and heterologous equine infectious anemia virus infection in horses with severe combined immunodeficiency.

Authors:  Sandra D Taylor; Steven R Leib; Wuwei Wu; Robert Nelson; Susan Carpenter; Robert H Mealey
Journal:  J Virol       Date:  2011-05-04       Impact factor: 5.103

2.  Immune reconstitution prevents continuous equine infectious anemia virus replication in an Arabian foal with severe combined immunodeficiency: lessons for control of lentiviruses.

Authors:  R H Mealey; D G Fraser; J L Oaks; G H Cantor; T C McGuire
Journal:  Clin Immunol       Date:  2001-11       Impact factor: 3.969

3.  Selection of a rare neutralization-resistant variant following passive transfer of convalescent immune plasma in equine infectious anemia virus-challenged SCID horses.

Authors:  Sandra D Taylor; Steven R Leib; Susan Carpenter; Robert H Mealey
Journal:  J Virol       Date:  2010-04-14       Impact factor: 5.103

4.  Cloning and large-scale expansion of epitope-specific equine cytotoxic T lymphocytes using an anti-equine CD3 monoclonal antibody and human recombinant IL-2.

Authors:  Robert H Mealey; Matt H Littke; Steven R Leib; William C Davis; Travis C McGuire
Journal:  Vet Immunol Immunopathol       Date:  2007-04-08       Impact factor: 2.046

5.  Failure of low-dose recombinant human IL-2 to support the survival of virus-specific CTL clones infused into severe combined immunodeficient foals: lack of correlation between in vitro activity and in vivo efficacy.

Authors:  Robert H Mealey; Matt H Littke; Steven R Leib; William C Davis; Travis C McGuire
Journal:  Vet Immunol Immunopathol       Date:  2007-07-25       Impact factor: 2.046

6.  Persistent cryptosporidiosis in horses with severe combined immunodeficiency.

Authors:  J M Bjorneby; D R Leach; L E Perryman
Journal:  Infect Immun       Date:  1991-10       Impact factor: 3.441

7.  Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection.

Authors:  Robert H Mealey; Steven R Leib; Sarah L Pownder; Travis C McGuire
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

8.  Immune responses are required to terminate viremia in equine infectious anemia lentivirus infection.

Authors:  L E Perryman; K I O'Rourke; T C McGuire
Journal:  J Virol       Date:  1988-08       Impact factor: 5.103

9.  Lymphocytes and macrophages are infected by Theileria equi, but T cells and B cells are not required to establish infection in vivo.

Authors:  Joshua D Ramsay; Massaro W Ueti; Wendell C Johnson; Glen A Scoles; Donald P Knowles; Robert H Mealey
Journal:  PLoS One       Date:  2013-10-07       Impact factor: 3.240

10.  Investigation of Known Genetic Mutations of Arabian Horses in Egyptian Arabian Foals with Juvenile Idiopathic Epilepsy.

Authors:  M Aleman; C J Finno; K Weich; M C T Penedo
Journal:  J Vet Intern Med       Date:  2017-11-24       Impact factor: 3.333
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