Literature DB >> 7427442

Collecting and banking human milk: to heat or not to heat?

B Björkstén, L G Burman, P De Château, B Fredrikzon, L Gothefors, O Hernell.   

Abstract

Data on human breast milk and its handling when fed to babies who cannot be breast-fed were reviewed to determine whether the method of processing and storage affected the properties of the milk. Breast milk is normally contaminated by potential pathogens, which seem to produce no ill effects, but it also contains antimicrobial properties which protect against infection. The evidence suggests that pasteurisation not only eliminates pathogenic bacteria but also damages bacteriostatic mechanisms, so making the milk more susceptible to later contamination. Pasteurisation also affects the nutritional properties of milk. Freezing has little effect on milk proteins, while a study on the effect of refrigeration showed that there was little bacterial growth at temperatures below 8 degrees C. Several years' experience of feeding donated raw milk to newborn infants has confirmed that it produces no ill effects. These findings suggest that pasteurisation of donated breastmilk is unnecessary, and it is not recommended, while the decision whether or not to freeze the milk may be made on practical grounds. Raw breast milk can be safely stored at 4-6 degrees C for 72 hours.

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Year:  1980        PMID: 7427442      PMCID: PMC1714023          DOI: 10.1136/bmj.281.6243.765

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  35 in total

1.  Herpes simplex virus in breast milk.

Authors:  S Kibrick
Journal:  Pediatrics       Date:  1979-09       Impact factor: 7.124

2.  Bile salt-stimulated lipase in human milk: evidence of activity in vivo and of a role in the digestion of milk retinol esters.

Authors:  B Fredrikzon; O Hernell; L Bläckberg; T Olivecrona
Journal:  Pediatr Res       Date:  1978-11       Impact factor: 3.756

Review 3.  A review. Fat digestion in the newborn: role of lingual lipase and preduodenal digestion.

Authors:  M Hamosh
Journal:  Pediatr Res       Date:  1979-05       Impact factor: 3.756

4.  Recurrent group B streptococcal disease in an infant associated with the ingestion of infected mother's milk.

Authors:  J F Kenny
Journal:  J Pediatr       Date:  1977-07       Impact factor: 4.406

5.  Loss of viability and metabolic injury of Staphylococcus aureus resulting from storage at 1 degree, 3 degrees, 5 degrees and 7 degrees C.

Authors:  T E Patterson; H Jackson
Journal:  J Appl Bacteriol       Date:  1979-02

6.  Human milk lipases. II. Bile salt-stimulated lipase.

Authors:  O Hernell; T Olivecrona
Journal:  Biochim Biophys Acta       Date:  1974-11-18

7.  Bacterial contamination of expressed breast milk.

Authors:  C L Jones; R F Jennison; S W D'Souza
Journal:  Br Med J       Date:  1979-11-24

8.  Alterations in tRNAs containing 2-methylthio-N6-(delta2-isopentenyl)-adenosine during growth of enteropathogenic Escherichia coli in the presence of iron-binding proteins.

Authors:  E Griffiths; J Humphreys
Journal:  Eur J Biochem       Date:  1978-01-16

9.  Equivalence of pasteurized and fresh human milk in promoting nitrogen retention by normal full-term infants.

Authors:  S J FOMON; L N THOMAS; C D MAY
Journal:  Pediatrics       Date:  1958-11       Impact factor: 7.124

10.  Use of Semliki forest virus to identify lipid-mediated antiviral activity and anti-alphavirus immunoglobulin A in human milk.

Authors:  J K Welsh; I J Skurrie; J T May
Journal:  Infect Immun       Date:  1978-02       Impact factor: 3.441

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  20 in total

Review 1.  Cytomegalovirus transmission from breast milk in premature babies: does it matter?

Authors:  P Bryant; C Morley; S Garland; N Curtis
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2002-09       Impact factor: 5.747

2.  Human milk banking: current concepts.

Authors:  N R Mehta; K N Subramanian
Journal:  Indian J Pediatr       Date:  1990 May-Jun       Impact factor: 1.967

3.  BSSL and PLRP2: key enzymes for lipid digestion in the newborn examined using the Caco-2 cell line.

Authors:  Eva-Lotta Andersson; Olle Hernell; Lars Bläckberg; Helen Fält; Susanne Lindquist
Journal:  J Lipid Res       Date:  2011-08-24       Impact factor: 5.922

Review 4.  Microbial contact during pregnancy, intestinal colonization and human disease.

Authors:  Samuli Rautava; Raakel Luoto; Seppo Salminen; Erika Isolauri
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-08-14       Impact factor: 46.802

5.  Hydrolysis of human milk fat globules by pancreatic lipase: role of colipase, phospholipase A2, and bile salts.

Authors:  L Bläckberg; O Hernell; T Olivecrona
Journal:  J Clin Invest       Date:  1981-06       Impact factor: 14.808

6.  Rate of inactivation of cytomegalovirus in raw banked milk during storage at -20 degrees C and pasteurisation.

Authors:  H Friis; H K Andersen
Journal:  Br Med J (Clin Res Ed)       Date:  1982-12-04

7.  Effect of Freezing Time on Tissue Factor Activity and Macronutrients of Human Milk.

Authors:  Begüm Gürel Gökmen; Ozan Özcan; Hava Taslak; Necla Ipar; Tuğba Tunali-Akbay
Journal:  Protein J       Date:  2020-09-28       Impact factor: 2.371

8.  Is ingestion of milk-associated bacteria by premature infants fed raw human milk controlled by routine bacteriologic screening?

Authors:  B J Law; B A Urias; J Lertzman; D Robson; L Romance
Journal:  J Clin Microbiol       Date:  1989-07       Impact factor: 5.948

9.  Impact of pasteurization on the antibacterial properties of human milk.

Authors:  Marjan Van Gysel; Veerle Cossey; Steffen Fieuws; Annette Schuermans
Journal:  Eur J Pediatr       Date:  2012-05-12       Impact factor: 3.183

10.  Oral microbial profile discriminates breast-fed from formula-fed infants.

Authors:  Pernilla L Holgerson; Nelly R Vestman; Rolf Claesson; Carina Ohman; Magnus Domellöf; Anne C R Tanner; Olle Hernell; Ingegerd Johansson
Journal:  J Pediatr Gastroenterol Nutr       Date:  2013-02       Impact factor: 2.839

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