| Literature DB >> 7426978 |
Abstract
Twelve male patients with urolithiasis were treated with 300 mg allopurinol daily. Urinary urate decreased from 251 +/- 55 to 156 +/- 19 (mean +/- SD) mmol per mol creatinine. The inhibition of calcium oxalate crystal growth was measured in an in vitro system and the inhibition index increased from 0.51 +/- 0.06 to 0.57 +/- 0.08 (mean +/- SD). Urinary citrate excretion was unaffected by the treatment.Entities:
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Year: 1980 PMID： 7426978 DOI： 10.1111/j.1464-410x.1980.tb02957.x
Source DB: PubMed Journal: Br J Urol ISSN： 0007-1331