Literature DB >> 7426831

Oxotremorine does not enhance acetylcholine release from rat diaphragm preparations.

C B Gundersen, D J Jenden.   

Abstract

We have reinvestigated the dramatic effect of oxotremorine on acetylcholine release from the rat diaphragm reported by Das, Ganguly & Vedasiromoni (1978), using a rigorous gas chromatographic mass spectrometric/isotope dilution method for identification and measurement of acetylcholine and choline. Oxotremorine (10 microM) causes no significant change in the spontaneous or evoked (1 or 10 Hz) release or in the tissue levels of acetylcholine or choline.

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Year:  1980        PMID： 7426831      PMCID： PMC2044364          DOI： 10.1111/j.1476-5381.1980.tb10897.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  8 in total

1.  Plasma choline: its turnover and exchange with brain choline.

Authors:  J J Freeman; R L Choi; D J Jenden
Journal:  J Neurochem       Date:  1975-04       Impact factor: 5.372

2.  AN IMPROVED SYNTHESIS OF OXOTREMORINE.

Authors:  A BEBBINGTON; D SHAKESHAFT
Journal:  J Med Chem       Date:  1965-03       Impact factor: 7.446

3.  The identification of an active metabolite of tremorine.

Authors:  A K CHO; W L HASLETT; D J JENDEN
Journal:  Biochem Biophys Res Commun       Date:  1961-07-26       Impact factor: 3.575

4.  Enhancement by oxotremorine of acetylcholine release from the rat phrenic nerve.

Authors:  M Das; D K Ganguly; J R Vedasiromoni
Journal:  Br J Pharmacol       Date:  1978-02       Impact factor: 8.739

5.  Simultaneous measurement of endogenous and deuterium-labeled tracer variants of choline and acetylcholine in subpicomole quantities by gas chromatography-mass spectrometry.

Authors:  D J Jenden; M Roch; R A Booth
Journal:  Anal Biochem       Date:  1973-10       Impact factor: 3.365

6.  The effect of atropine upon acetylcholine release from cat superior cervical ganglia and rat cortical slices: measurement by a radio-enzymic method.

Authors:  A C Kato; B Collier; D Ilson; J M Wright
Journal:  Can J Physiol Pharmacol       Date:  1975-12       Impact factor: 2.273

7.  Inhibition by oxotremorine of acetylcholine resting release from guinea pig-ileum longitudinal muscle strips.

Authors:  H Kilbinger; P Wagner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

8.  Stimulating action of atropine on the release of acetylcholine by rat cerebral cortex in vitro.

Authors:  R L Polak
Journal:  Br J Pharmacol       Date:  1971-04       Impact factor: 8.739
  8 in total
  9 in total

1.  Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.

Authors:  G T Somogyi; E S Vizi; I A Chaudhry; H Nagashima; D Duncalf; F F Foldes; P L Goldiner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-07       Impact factor: 3.000

2.  The effects of muscarine and atropine reveal that inhibitory autoreceptors are present on frog motor nerve terminals but are not activated during transmission.

Authors:  M S Arenson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-02       Impact factor: 3.000

3.  Phenthonium, a quaternary derivative of (-)-hyoscyamine, enhances the spontaneous release of acetylcholine at rat motor nerve terminals.

Authors:  M L Fann; C Souccar; A J Lapa
Journal:  Br J Pharmacol       Date:  1990-07       Impact factor: 8.739

4.  Facilitatory and inhibitory muscarine receptors on the rat phrenic nerve: effects of pirenzepine and dicyclomine.

Authors:  I Wessler; A Diener; M Offermann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-08       Impact factor: 3.000

5.  Muscarine receptors on the rat phrenic nerve, evidence for positive and negative muscarinic feedback mechanisms.

Authors:  I Wessler; M Karl; M Mai; A Diener
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-06       Impact factor: 3.000

6.  Prejunctional modulation of acetylcholine release from the skeletal neuromuscular junction: link between positive (nicotinic)- and negative (muscarinic)-feedback modulation.

Authors:  E S Vizi; G T Somogyi
Journal:  Br J Pharmacol       Date:  1989-05       Impact factor: 8.739

7.  Release of acetylcholine at the motor endplate of the rat - evidence against a muscarinic acetylcholine autoreceptor.

Authors:  J Häggblad; E Heilbronn
Journal:  Br J Pharmacol       Date:  1983-11       Impact factor: 8.739

8.  Release of [3H]acetylcholine from a modified rat phrenic nerve-hemidiaphragm preparation.

Authors:  I Wessler; H Kilbinger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-12       Impact factor: 3.000

9.  The effects of atropine and oxotremorine on acetylcholine release in rat phrenic nerve-diaphragm preparations.

Authors:  E T Abbs; D N Joseph
Journal:  Br J Pharmacol       Date:  1981-06       Impact factor: 8.739
  9 in total

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