Literature DB >> 7426582

The congenital warfarin syndrome: a case report.

M Baillie, E D Allen, A R Elkington.   

Abstract

A case is reported of a baby born with congenital abnormalities due to maternal ingestion of warfarin during pregnancy. Warfarin is known to be teratogenic, producing characteristic abnormalities, namely a hypoplastic nose, stippled epiphyses, and skeletal abnormalities. A variety of ocular abnormalities have been reported. Ophthalmologists should seek a history of maternal warfarin ingestion when seeing a baby with congenital ocular abnormalities. They should also be aware of the possible teratogenic effects when considering warfarin therapy for a woman of childbearing age.

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Year:  1980        PMID: 7426582      PMCID: PMC1043772          DOI: 10.1136/bjo.64.8.633

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  8 in total

1.  Chondrodysplasis punctata: is maternal warfarin therapy a factor?

Authors:  M H Becker; N B Genieser; M Finegold; D Miranda; T Spackman
Journal:  Am J Dis Child       Date:  1975-03

2.  The use of anticoagulants for thrombophlebitis during pregnancy.

Authors:  G QUENNEVILLE; B BARTON; E McDEVITT; I S WRIGHT
Journal:  Am J Obstet Gynecol       Date:  1959-05       Impact factor: 8.661

Review 3.  THROMBOEMBOLIC DISEASE IN PREGNANCY.

Authors:  U VILLASANTA
Journal:  Am J Obstet Gynecol       Date:  1965-09-01       Impact factor: 8.661

4.  Pregnancy in a patient with a prosthetic mitral valve. Associated with a fetal anomaly attributed to warfarin sodium.

Authors:  I J Kerber; O S Warr; C Richardson
Journal:  JAMA       Date:  1968-01-15       Impact factor: 56.272

5.  Multiple congenital anomalies associated with oral anticoagulants.

Authors:  W L Shaul; J G Hall
Journal:  Am J Obstet Gynecol       Date:  1977-01-15       Impact factor: 8.661

6.  Warfarin as a possible teratogen.

Authors:  D T Fourie; I T Hay
Journal:  S Afr Med J       Date:  1975-11-22

7.  Warfarin therapy initiated during pregnancy and phenotypic chondrodysplasia punctata.

Authors:  R M Pauli; J D Madden; K J Kranzler; W Culpepper; R Port
Journal:  J Pediatr       Date:  1976-03       Impact factor: 4.406

8.  Congenital malformations associated with the administration of oral anticoagulants during pregnancy.

Authors:  J M Pettifor; R Benson
Journal:  J Pediatr       Date:  1975-03       Impact factor: 4.406

  8 in total

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